Pilot Travel Center #429 Florence

What they do. Who they serve.

Pilot Travel Center #429 sits on US-43 in Florence, Alabama, serving north-south freight moving between the Tennessee Valley and the Gulf Coast. Open around the clock, this location provides diesel fuel, dedicated truck parking, and the standard Pilot Flying J amenities drivers expect on long corridor runs through the Shoals region. The stop anchors the northwest corner of Alabama where US-43 meets Interstate 65 traffic filtering through the state, making it a practical refuel and rest point for haulers working Birmingham, Huntsville, and Memphis routes. With 24/7 access and ample parking, this Florence Pilot works well for drivers needing a straightforward fuel-and-go or an overnight spot between major metros. The facility handles steady regional and OTR volume, offering a reliable midpoint for teams running the I-65 corridor and owner-operators managing tight schedules through north Alabama.