TravelCenters of America - Santee

What they do. Who they serve.

TravelCenters of America in Santee sits just off I-95 near the Manning exit, serving northbound and southbound freight on one of the East Coast's busiest commercial corridors. Open around the clock, this TA offers diesel fuel, truck parking, and a full-service repair shop—critical for drivers running the I-95 spine between Florida and the Mid-Atlantic. The location handles everything from routine maintenance to roadside breakdowns, with amenities including showers and laundry to support long-haul runs. Santee's position between Charleston and Columbia makes it a natural refuel and rest point for regional and over-the-road drivers alike. Whether you're hauling produce north or manufactured goods south, this stop provides the fuel, parking, and shop services needed to keep moving on I-95. With more than 1,200 driver reviews, it's a proven waypoint for the trucking community working this heavy freight lane.